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Efeitos do consumo de ácidos graxos n-3, n-6 e trans sobre aspectos bioquímicos e moleculares em um modelo animal de mania
(Universidade Federal de Santa Maria, 2014-07-18)
Fatty acids (FA) are constituents of neuronal phospholipid membranes, where they are essential for the development and functioning of the brain. During the peak of neuronal growth, occurring during the last week of gestation ...
Atividade anestésica de óleos essenciais e constituintes isolados de plantas medicinais brasileiras em Rhamdia quelen
(Universidade Federal de Santa Maria, 2014-01-13)
The aim of this study was to obtain new fish anesthetic and sedative drugs from Brazilian
medicinal plants: Ocimum gratissimum (OG), Ocimum americanum (OA) e Hyptis mutabilis
(HM). Essential oils from these plants were ...
Efeito do tucumã (Astrocaryum aculeatum, Meyer) na citoproteção causada pelo estresse oxidativo e na modulação de células de leucemia promielocítica aguda
(Universidade Federal de Santa Maria, 2014-12-17)
Carotenoids are natural pigments soluble inversely associated with risk of a variety of
diseases. In the Amazon region there is a wide variety of native fruits which are rich in
carotenoids, which functional properties ...
Efeito farmacogenômico in vitro do Astrocaryum aculeatum em células mononucleares do sangue periférico e de câncer de mama
(Universidade Federal de Santa Maria, 2014-01-21)
Breast cancer, due to their prevalence in our environment and global public health is a disease subject of numerous contemporary studies. Some of these studies suggest that certain genes related to cell cycle and apoptosis ...
Efeitos dos extratos de Solanum guaraniticum e Syzygium jambos sobre parâmetros bioquímicos e de estresse oxidativo em modelos in vitro e in vivo
(Universidade Federal de Santa Maria, 2014-01-22)
The use of medicinal plants for the treatment and prevention of disease is a common
practice, despite their effects are few studied scientifically. Solanum guaraniticum, also known as
false jurubeba, is a medicinal plant ...
Influência de estrógenos e progestinas sobre a atividade da superóxido dismutase e o estatus oxidativo em mulheres
(Universidade Federal de Santa Maria, 2013-05-20)
The deficit of estrogen that accompanies menopause may be involved in the metabolic changes and increased oxidative stress during non-reproductive female life. Hormone replacement therapy (HRT) has been used to attenuate ...
Ação protetora do licopeno sobre as alterações induzidas pela micotoxina zearalenona em camundongos machos
(Universidade Federal de Santa Maria, 2014-12-22)
Zearalenone (ZEA) an estrogenic mycotoxin and, therefore the reproductive system as one of its main targets of toxicity. Besides being a mycotoxin and toxigenic immunosuppressive, the ZEA hematological changes and promotes ...
Efeitos neuroendócrinos e comportamentais do aripiprazol em zebrafish
(Universidade Federal de Santa Maria, 2019-01-17)
The aripiprazole (APPZ) is a second-generation atypical antipsychotic, which has been
increasingly used in the treatment of psychoses, such as schizophrenia, autism, bipolar
affective disorder, among others. The increasing ...
Consequências da modulação farmacológica da Na+, K+ - ATPase na epilepsia induzida por pilocarpina
(Universidade Federal de Santa Maria, 2018-08-24)
Epilepsy is one of the most common chronic neurological diseases worldwide, and despite a variety of drugs introduced into clinical practice, one-third of patients remain unresponsive to therapies. In addition, when ...
Caracterização química e avaliação das atividades antimicrobiana, antinociceptiva e anti-inflamatória do própolis da Melipona quadrifasciata quadrifasciata
(Universidade Federal de Santa Maria, 2018-05-10)
The demand for natural products with biological application has become of great interest of
the scientific community and is not different from the products produced by the bees: honey,
propolis, wax and pollen. Several ...