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Efeitos do aspartame e do orlistate em animais saudáveis e com doença gordurosa do fígado associada a disfunção metabólica: parâmetros bioquímicos, metabólicos e oxidativos
(Universidade Federal de Santa Maria, 2023-01-18)
This thesis evaluated the effects of chronic administration of aspartame (ASP), as well as investigated
the effects of ASP, orlistat, and their association in the liver of healthy mice and mice with metabolicassociated ...
Avaliação do efeito do beta-cariofileno após status epilepticus induzido por pilocarpina em ratos
(Universidade Federal de Santa Maria, 2023-01-27)
Epilepsy is a chronic brain disease characterized by an enduring predisposition to generate
epileptic seizures. Epilepsy has serious neurological, cognitive, psychological, and social
consequences. Status epilepticus(SE) ...
Biodisponibilidade e distribuição tecidual de compostos fenólicos do mirtilo (Vaccinium sp.) obtidos com solvente eutético profundo natural
(Universidade Federal de Santa Maria, 2023-02-01)
Natural deep eutectic solvents (NADES) are biosustainable solvents proposed as a safe
alternative for obtaining bioactive extracts. Despite the low absorption, the phytochemicals
widely present in the blueberry, have ...
O exercício físico reduz parâmetros comportamentais e moleculares envolvidos na drogadição por anfetamina em ratos: envolvimento da via opioide endógena
(Universidade Federal de Santa Maria, 2023-09-15)
The mesolimbic dopaminergic system constitutes a drug target circuit, whose neuroplasticity
alteration is involved in the development of drug addiction. Due to this neuromodulation,
currently available treatments only ...
Prescrição de fármacos inapropriados em idosos hospitalizados: análise da mortalidade e sobrevida
(Universidade Federal de Santa Maria, 2023-09-29)
Introduction: Elderly people (>60 years old) have a high prevalence of chronic noncommunicable diseases (DCNTs), often managed through the daily use of four or more
drugs (polypharmacy). Furthermore, they may present ...
Consequências da exposição ao levonorgestrel em zebrafish: efeitos persistentes e transgeracionais
(Universidade Federal de Santa Maria, 2023-09-18)
The consumption of contraceptive medications such as levonorgestrel (LNG) has
increased considerably in recent decades, and consequently its disposal in the
environment, and it has already been detected in different ...
Influência da dose de cetamina e da pioglitazona em sintomas tipo-esquizofrenia e marcadores bioquímicos em camundongos
(Universidade Federal de Santa Maria, 2023-10-31)
Schizophrenia is a severe mental illness characterized by positive, negative and cognitive symptoms, whose etiology is not fully elucidated, being cognitive symptoms difficult to treat. Ketamine is a non-competitive NMDA ...
Efeitos do R-(+)-limoneno na dieta sobre o crescimento, metabolismo, estresse e respostas antioxidantes de peixes infectados ou não com Aeromonas hydrophila
(Universidade Federal de Santa Maria, 2023-12-12)
Intensive fish farming can lead to stressful situations that affect their growth. Aeromonas
hydrophila is a challenging pathogen for the productive success of fish. In addition to causing
outbreaks with mass death of ...