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Estresse oxidativo e metabolismo ósseo em modelo roedor de síndrome dos ovários policísticos (SOP)
(Universidade Federal de Santa Maria, 2020-12-18)
Polycystic ovary syndrome (PCOS) is considered the commonest cause of endocrine infertility in women and affects around 8% of females at reproductive age. It is a complex disturbance, frequently associated with insulin ...
Avaliação da Vanillosmopsis arborea Baker e (-)-α-bisabolol frente a parâmetros oxidativos e toxicológicos
(Universidade Federal de Santa Maria, 2017-08-18)
Vanillosmopsis arborea Baker belongs to the Asteraceae family and has a recognized economic value due to its anti-inflammatory properties, derived from sesquiterpene (-)-α-bisabolol (BISA), which is present in high ...
Avaliação da atividade antinociceptiva do extrato e do alcaloide s-(+)-dicentrina extraído de frutos de Ocotea puberula (Lauraceae)
(Universidade Federal de Santa Maria, 2012-12-18)
Ocotea puberula (Lauraceae) is a brazilian native tree, known in the South regions as canela guaicá or canela amarela. Its phytochemical composition includes several alkaloids of aporphinic type, some of them with biological ...
Avaliação das propriedades farmacológicas e farmacogenéticas do extrato e frações da planta Pavonia xanthogloea (Malvaceae)
(Universidade Federal de Santa Maria, 2014-01-31)
The Pampa Biome has a great biodiversity of plants, among them the Family Malvaceae. Despite the medicinal use of many of these plants, studies on the biological activity of these are still very scarce. This is the case ...
A ação anti-inflamatória do lítio é influenciada por fatores genéticos, nutricionais e fármacos antidepressivos: estudos in vitro
(Universidade Federal de Santa Maria, 2017-09-01)
Population aging has increased the prevalence of chronic non-communicable diseases, including psychiatric disorders such as depression and bipolar spectrum disorders (BSDs). Evidence suggests that such disorders are ...
Influência de fatores farmacológicos e nutricionais na resposta oxidativa-inflamatória in vitro induzida pela olanzapina
(Universidade Federal de Santa Maria, 2019-03-13)
Introduction: Olanzapine (OLZ) is a second generation antipsychotic (ASG) used in the treatment of
schizophrenia, bipolar disorder and other neuropsychiatric conditions. The adverse effects of ASG
include ...
Propriedades neurofarmacológicas da Euterpe oleracea: estudo in vitro do potencial uso no tratamento de doenças psiquiátricas
(Universidade Federal de Santa Maria, 2017-01-26)
Introduction: Neuropsychiatric diseases, as bipolar disorder (BD), have a very complex pathophysiology. Several times the diagnostic and to choose a correct treatment are difficult. Currently, have been developed studies ...
Efeito do antipsicótico haloperidol em Caenorhabditis elegans e do extrato bruto de Piper methysticum em camundongos sobre parâmetros comportamentais e bioquímicos
(Universidade Federal de Santa Maria, 2021-08-31)
Psychotic disorders, as schizophrenia and substance-induced psychoses (amphetamine, for example), are characterized by the appearance of delusions, hallucinations and other, and their symptoms are associated with hyperactivation ...
Farmacocinética de S-(+)-linalol em jundiás (Rhamdia quelen)
(Universidade Federal de Santa Maria, 2021-06-18)
S-(+)-linalool is found in essential oils of aromatic plants as Lippia alba. This phytochemical had its sedative/anesthetic activity elucidated in Rhamdia quelen, popularly known as silver catfish. Thus, S-(+)-linalool has ...
Suscetibilidade in vitro de Prototheca spp., isoladas de leite bovino, aos óleos essenciais, aos peptídeos e fármacos antimicrobianos
(Universidade Federal de Santa Maria, 2021-03-19)
Alchlorophilic algae of the genus Prototheca are disease-causing agents in humans and animals. The species Prototheca zopfii (genotype 2), with recent reclassification suggested for P. bovis, is cited by several authors ...