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Avaliação dos efeitos do tratamento crônico com neurolépticos e sua interação com substâncias potencialmente antioxidantes sobre parâmetros de estresse oxidativo no fígado e rim de ratos
(Universidade Federal de Santa Maria, 2008-03-27)
Treatment with neuroleptic drugs has been associated to side effects like tardive diskynesia and hepatic damage. In spite of the several reports of hepatotoxicity after neuroleptic administration, few data are available ...
Biomarcadores de estresse oxidativo em carpas (Cyprinus carpio) expostas aos inseticidas carbofuran e fipronil em condições de lavoura de arroz
(Universidade Federal de Santa Maria, 2009-07-24)
The contamination of the aquatic environment by pesticides is a problem of global importance because of their toxic effect on non-target organisms. These products may affect toxicological parameters and oxidative stress ...
Medida da atividade de ectonucleotidases e indicadores do estresse oxidativo em pacientes com infarto agudo do miocárdio
(Universidade Federal de Santa Maria, 2008-03-07)
Acute Myocardial Infarction (AMI) is one of the major public health problems in the world. Coronary occlusion, which occurs when an atherosclerotic plaque breaks, is the main mechanism that leads to AMI. With the objective ...
Óleos essenciais alteram parâmetros comportamentais e bioquímicos em diferentes espécies de crustáceos?
(Universidade Federal de Santa Maria, 2021-08-30)
Crustaceans integrate essential ecosystem functions in the enviroment, acting from primary
consumers to predators in aquatic trophic networks. Furthermore, many decapod crustaceans
are important economic and social ...
Estudo da ação antipsicótica e efeitos colaterais do haloperidol nanoencapsulado em ratos
(Universidade Federal de Santa Maria, 2012-06-29)
Haloperidol is a typical neuroleptic widely used in the treatment of several psychotic disorders and it remains the most prescribed antipsychotic worldwide, due to its high potency and low cost. Despite its good therapeutic ...
Dexmedetomidina diminui a resposta inflamatória após cirurgia miocárdica sob mini-circulação extracorpórea
(Universidade Federal de Santa Maria, 2013-03-09)
Despite great technological advances in coronary artery bypass grafting (CABG) surgery, there is a high incidence of cardiac dysfunction and neurocognitive deficits in the postoperative period. Preventive measures are ...
Avaliação da atividade da isatina-3-N4-benziltiossemicarbazona (IBTC) como antioxidante na proteção da LDL contra a oxidação
(Universidade Federal de Santa Maria, 2012-08-10)
Several lines of evidence support the hypotheses that the oxidation of low density lipoprotein (LDL) is a proatherogenic factor. Oxidative stress is one of the causes of the overproduction of reactive species that increase ...
Produtos apícolas como antioxidantes em peixes frente a desafios oxidantes provocados por tebuconazole
(Universidade Federal de Santa Maria, 2013-10-25)
This paper present alternatives to mitigate the deleterious effects caused by pesticides from
crops that contaminate ponds and water bodies, located very close to the growing areas. This
proximity causes oxidative damage ...
2,2'-Disseleneto de ditienila, um composto orgânico de selênio com atividade antioxidante e neuroprotetora em ratos
(Universidade Federal de Santa Maria, 2012-03-02)
Oxidative stress has been implicated in the pathophysiology of several neurological
diseases since the brain is an organ highly susceptible to oxidative damage. Temporal lobe
epilepsy (TLE) has been widely studied due ...
Interações entre o estresse repetido e clomipramina: diferentes respostas em ratos machos e fêmeas
(Universidade Federal de Santa Maria, 2011-10-14)
Repeated stress or stressful events has been reported to induce anxiety and depression. Differential
responses to repeated stress and antidepressant treatments have been observed in males and females.
Clomipramine is a ...