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Atividade do óleo de Cymbopogon flexuosus livre e nanoestruturado frente a micobactérias de crescimento rápido
(Universidade Federal de Santa Maria, 2018-02-28)
Rapidly Growing Mycobacteria (RGM) are emerging pathogens responsible for various
human infections, although they are often considered only as contaminants or colonizers. The
formation of biofilms by these ...
Desenvolvimento de nanocápsulas poliméricas com diferentes revestimentos para a liberação cerebral de vimpocetina
(Universidade Federal de Santa Maria, 2018-02-02)
Vinpocetine (VP) is used in neurodegenerative diseases, and researches have
indicated a promising anticonvulsant effect of this drug. However, it shows some limitations as
low aqueous solubility and short half-life. ...
Avaliação anti-inflamatória e antioxidante do extrato de tucumã (Astrocaryum aculeatum): estudos in vitro e in vivo
(Universidade Federal de Santa Maria, 2018-01-19)
With the rise of new concepts such as functional foods, nutraceuticals and phytomedicines, allied to the use of traditional medicine, products of plant origin are in evidence. Brazil is a highlight in the development of ...
Avaliação de parâmetros de estresse oxidativo em gestantes gemelares
(Universidade Federal de Santa Maria, 2018-01-05)
Twin pregnancies are considered to be of high obstetric risk due to several morbidities frequently present due to the increased supply of metabolic compounds to fetuses and the high oxygen consumption by the fetus-placenta ...
Desenvolvimento e validação de métodos analíticos para controle de qualidade de comprimidos de empagliflozina e estudo preliminar de estabilidade
(Universidade Federal de Santa Maria, 2018-03-27)
Diabetes mellitus (DM) is a disease characterized by a heterogeneous group of metabolic disorders, which present hyperglycemia in common. Different classes of oral antidiabetics, such as empagliflozin, belonging to the ...
Atividade antimicobacteriana, antibiofilme e avaliação da toxicidade in vitro de complexos metálicos do sulfametoxazol
(Universidade Federal de Santa Maria, 2018-03-05)
Rapidly growing mycobacteria (RGM) are opportunistic microorganisms, found in the
environment, that can cause both local and disseminated infections. RGM can form structured
communities that adhere to solid ...
Redirecionamento de fármacos e sinergia de medicamentos não-antibióticos e antibióticos no tratamento de doenças infecciosas
(Universidade Federal de Santa Maria, 2018-09-13)
The indiscriminate use of antimicrobials in monotherapy has led to the emergence of
multiresistant bacterial strains, which are also one of the greatest threats to human health.
Whiles antibiotic resistance presents ...
Atividade antimicrobiana de extratos de Maclura tinctoria (L) D. Don ex Steud contra patógenos de peixes
(Universidade Federal de Santa Maria, 2018-07-27)
The sanitary conditions to which the animals are submitted in aquaculture are often
inadequate, being stressing factors triggering pathological processes as bacterial infections. In
this context, bacterial ...
Desenvolvimento de uma formulação farmacêutica para uso tópico, análise fitoquímica e farmacológica de Persea americana Mill. (Lauraceae)
(Universidade Federal de Santa Maria, 2018-07-04)
The species Persea americana Mill., belonging to the Lauraceae family is known in popular
medicine as avocado. Several pharmacological effects attributed to this species have been
described in the ...