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Efeito do beta-cariofileno na suscetibilidade hepática e renal à aflatoxina B1 em parâmetros bioquímicos, oxidativos e moleculares em ratos
(Universidade Federal de Santa Maria, 2021-08-13)
Aflatoxin B1 (AFB1) is a mycotoxin produced manly by Aspergillus flavus and Aspergillus
parasiticus fungi. Among the existing mycotoxins, AFB1 has been the most studied due to its
high toxigenic potential. Exposure to ...
Farmacocinética de S-(+)-linalol em jundiás (Rhamdia quelen)
(Universidade Federal de Santa Maria, 2021-06-18)
S-(+)-linalool is found in essential oils of aromatic plants as Lippia alba. This phytochemical had its sedative/anesthetic activity elucidated in Rhamdia quelen, popularly known as silver catfish. Thus, S-(+)-linalool has ...
Suscetibilidade in vitro de Prototheca spp., isoladas de leite bovino, aos óleos essenciais, aos peptídeos e fármacos antimicrobianos
(Universidade Federal de Santa Maria, 2021-03-19)
Alchlorophilic algae of the genus Prototheca are disease-causing agents in humans and animals. The species Prototheca zopfii (genotype 2), with recent reclassification suggested for P. bovis, is cited by several authors ...
Fraturas ósseas em mulheres na pós-menopausa: um estudo de coorte em Santa Maria/RS
(Universidade Federal de Santa Maria, 2021-03-31)
Osteoporosis is characterized by low bone mass associated with abnormalities in bone microarchitecture, increasing the risk of fragility fractures. Although there are guidelines for the diagnosis and treatment of osteoporosis, ...
Eficácia, aceitabilidade e tolerabilidade do tratamento farmacológico do transtorno de estresse pós-traumático e dos antidepressivos na qualidade do sono de adultos com transtorno de estresse pós-traumático: revisões sistemáticas e metanálises em rede
(Universidade Federal de Santa Maria, 2021-08-25)
Pharmacological treatments for adults with post-traumatic stress disorder:
A network meta-analysis of comparative efficacy and acceptability.
Background: The purpose of this study was to compare efficacy and acceptability ...
Depressão: aspectos fisiopatológicos e o efeito tipo-antidepressivo da apocinina
(Universidade Federal de Santa Maria, 2020-02-17)
Depression is considered a public health challenge around the world. According to the World Health Organization, more than 300 million people (approximately 6% of the world population) are affected by this disorder. ...
Envolvimento do canal TRPA1 nos comportamentos do tipo depressivo e ansioso em um modelo de esclerose múltipla progressiva em camundongos
(Universidade Federal de Santa Maria, 2020-09-25)
Background and Purpose: Progressive multiple sclerosis (PMS) is a neurological disease associated with the development of depression and anxiety, and treatments available are unsatisfactory. The transient potential receptor ...
Efeito modulatório in vitro da quetiapina não-metabolizada na citotoxicidade e ativação inflamatória de células brancas e na formação de armadilhas extracelulares de neutrófilos
(Universidade Federal de Santa Maria, 2020-02-19)
Quetiapine (QUE) is a highly complex drug that, due to its different forms of interaction with receptors, has great clinical applicability. Although widely used, QUE brings with it a range of side effects that include, in ...
Relação entre o sistema imune e o comportamento em zebrafish
(Universidade Federal de Santa Maria, 2020-03-06)
The interaction between immune system and behavior has already been observed in several studies using mammals as animal model. On the other hand, this relationship has not yet been clearly demonstrated in other animal ...
Beta-cariofileno atenua dano cognitivo induzido pela exposição ao aspartame em ratos pela modulação da atividade da acetilcolinesterase e da Via BDNF/TrKB
(Universidade Federal de Santa Maria, 2021-08-26)
Aspartame (ASP) is a widely used as a tabletop sweetener and sucrose substitute in many
food matrices. However, several studies have reported that exposure to ASP can damage
biological tissues, such as the central nervous ...