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O extrato hidroalcóolico das folhas de Arachis hypogaea L (Fabaceae) produz atividade antioxidante e anti-inflamatória in vitro sem a indução de toxicidade in vitro ou in vivo
(Universidade Federal de Santa Maria, 2020-03-26)
Arachis hypogaea (peanut) leaves are traditionally used for the treatment of insomnia and inflammation. This study aimed to examine the phytochemical composition of peanut leaf hydroalcoholic extract (PLHE) and to describe ...
Caracterização da nocicepção em um modelo de dor do câncer de mama e avaliação da participação do receptor TRPA1 neste modelo em camundongos fêmeas
(Universidade Federal de Santa Maria, 2021-08-27)
Breast cancer can cause bone metastasis, contributing to patients' pain. There is still a portion of patients with breast cancer who have inadequate treatment for pain. The mechanisms associated with cancer pain are still ...
Minociclina e imunoterapia no tratamento da pitiose experimental em coelhos
(Universidade Federal de Santa Maria, 2020-03-31)
Pythiosis is a chronic disease caused by the oomycete Pythium insidiosum that
affects both animals and humans. The main animals affected are the equines and canines,
generating a worrying clinical picture. If not identified ...
Influência do sexo nas diferenças comportamentais promovidas pela exposição ao etanol em peixes-zebra submetidos à interação com um objeto não familiar
(Universidade Federal de Santa Maria, 2021-12-16)
In humans, ethanol (EtOH) modulates behavioral functions in a biphasic manner, ranging from disinhibition to sedation. The effects of EtOH are dose-dependent and influenced by environmental and individual factors, such as ...
Efeito neuroprotetor do JM-20 em ratos submetidos a traumatismo cranioencefálico leve
(Universidade Federal de Santa Maria, 2021-09-10)
Traumatic brain injury (TBI) is a multisystemic pathology with interactions between central nervous system, peripheral nervous system and immune system. It is one of the main causes of death and desability worldwide. The ...
Aplicações do óleo essencial de aloysia citriodora paláu e do citral adicionados à água e à dieta para jundiá e carpa-capim
(Universidade Federal de Santa Maria, 2020-03-20)
The present study deals with the effectiveness of citral added to water as a sedative and anesthetic in silver catfish (Rhamdia quelen) and grass carp (Ctenopharyngodon idella). It deals with the anesthetic safety of the ...
Influência do sistema adrenérgico na enzima Na+, K+- ATPase no aparecimento de fadiga em córtex de ratos
(Universidade Federal de Santa Maria, 2021-10-07)
Physical exercise brings health benefits, such as reducing neurological diseases and improving the immune system. Although exercise brings such benefits, it is also a stressor for the body, and may impact the immune and ...
Caracterização enzimática da e-ntpdase em linfócitos residentes de orgãos imunes primários, secundários e não imunes de ratos wistar
(Universidade Federal de Santa Maria, 2021-09-03)
Ectoenzymes play an important role in controlling the signaling developed by adenine nucleotides and nucleosides in countless cells. However, little information is found in the scientific literature about the biochemical ...
Efeitos do glifosato sobre o desenvolvimento embrionário, larval e adulto do peixe-zebra (Danio rerio)
(Universidade Federal de Santa Maria, 2021-09-16)
Glyphosate-Based Herbicides (GBH) are the most used pesticides in the world and pose risks to environmental health and to non-target organisms. This work aimed to verify the toxicity, the mechanisms involved and the ...
Mecanismos neurológicos e sistêmicos envolvidos na patogênese da listeriose e impactos do uso de curcumina livre e nanoencapsulada na infecção in vivo
(Universidade Federal de Santa Maria, 2021-10-27)
Foodborne zoonotic disease, listeriosis contains numerous gaps in knowledge regarding its pathogenic mechanisms. In addition, the problem of bacterial resistance requires potential alternatives to treatment. The aim of ...