The development of nanostructured materials has provided better control of the release and targeting of active substances to the treatment site, minimizing adverse effects, in addition to contributing to increased therapeutic ...

The thiosemicarbazone compounds are of considerable scientific interest because of their important biological and chemical properties, such as antitumor, antibacterial, antiviral, antiprotozoal, cytotoxic, among others. ...

Food and agricultural industries generate substantial quantities of phenolic-rich by-products that could be valuable natural sources of antioxidants. The aim of this study was to identify and quantify the phenolic compounds ...

The incidence of diabetes mellitus (DM) has increased, becoming a global public health problem. Approximately 415 million people worldwide have DM, causing chronic complications including changes in the state of blood ...

Gestational diabetes mellitus (GDM) is a glucose intolerance beginning during pregnancy. It is a common disorder and its incidence is increasing among pregnant women. Hyperglycemia derived from GDM is associated with the ...

The use of plants for therapeutic purposes is an ancient practice. In Brazil, the herbal medicine is very expressive due to a great plant biodiversity. The medicinal value attributed to some plants results from the presence ...

During pregnancy, even being a physiological process, there is an increase in oxidative stress due to increased metabolic demands and increased oxygen consumption in the tissues, especially in the placenta, in response to ...

Pain and inflammation are physiological processes, which when persist can be harmful to health. The pain when improperly or left untreated can become chronic pain. Moreover, the inflammation can be involved in the pathogenesis ...

Esophageal cancer is a tumor with a higher incidence in males, and it is highly fatal. Epidemiological data points out to consumption of tobacco and alcohol and the exposition to polycyclic aromatic hydrocarbon are the ...

Chronic myeloid leukemia (CML) results from the clonal proliferation of a hematopoietic stem cell representing approximately 15-20% of all cases of leukemia. It is characterized by the presence of the Philadelphia chromosome ...