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Descrição de isolado clínico de Bordetella trematum por sequenciamento de genoma total
(Universidade Federal de Santa Maria, 2019-07-18)
Bordetella trematum is a Gram-negative coccobacillus found in wounds, diabetic foot ulcers,
otitis, peritonitis and bacteremia. Usually it does not cause infections in humans. There are
few case reports described in the ...
Estudo da atividade antibacteriana, físico químicas farmacocinéticas e toxicológicas de novos compostos derivados de pirazolina
(Universidade Federal de Santa Maria, 2022-08-24)
Pseudomonas aeruginosa is an opportunistic bacterium that rarely causes infection in healthy people. However, it is among the main agents in nosocomial infections, with high rates of morbidity and mortality due to its ...
Hidrogel de base nanotecnológica contendo silibinina com ação anti-inflamatória no modelo de óleo de cróton
(Universidade Federal de Santa Maria, 2018-11-30)
Currently, irritant contact dermatitis is the most prevalent dermatitis among the others and is triggered
by the activation of innate immunity after skin contact with irritants. Silibinin (SB), a naturally occurring ...
Nanocápsulas de poli(ɛ-caprolactona) contendo vimpocetina: desenvolvimento e avaliação da atividade anticonvulsivante
(Universidade Federal de Santa Maria, 2017-02-13)
Epilepsy is a disease characterized by convulsive seizures, caused by an excessive neuronal electrical discharge, which affects 50 million people worldwide. Vinpocetine, derived from the alkaloid vincamine, is a neuroprotective ...
Atividade antifúngica, antibiofilme e antioxidante do óleo essencial de Citrus deliciosa Tenore
(Universidade Federal de Santa Maria, 2020-06-22)
Plants and their metabolites have been used in folk medicine for years to treat various diseases. Plant essential oils are volatile, lipophilic, and aromatic substances, presenting several therapeutic properties, which ...
Ebastina: obtenção de novas formas cristalinas e caracterização no estado sólido
(Universidade Federal de Santa Maria, 2015-12-04)
Ebastine (EBA) is a second-generation antihistamine with poor water solubility. It is used in the treatment of allergic rhinitis and chronic idiopathic urticaria. For oral administration of drugs, there is a preference for ...
Atividade antimicrobiana e antibiofilme de óleo de Thymus vulgaris frente à Streptococcus mutans
(Universidade Federal de Santa Maria, 2021-09-10)
The caries desease is still a major challenge, despite all the means available today for your treatment. The development of caries lesions in the oral cavity is the simultaneous combination of several factors, being ...
Vitis Vinifera L. cv Pinot Noir: bagaço e borra do vinho como potencial fonte de compostos bioativos
(Universidade Federal de Santa Maria, 2016-07-01)
Food and agricultural industries generate substantial quantities of phenolic-rich by-products
that could be valuable natural sources of antioxidants. The aim of this study was to identify
and quantify the phenolic compounds ...
Caracterização fenotípica e molecular da resistência a clindamicina em isolados clínicos de Staphylococcus aureus de um hospital terciário
(Universidade Federal de Santa Maria, 2016-08-11)
Staphylococcus aureus demonstrated over the time, the ability to develop resistance to the most antimicrobials. The mechanism of resistance to macrolides in S. aureus also reaches lincosamides and streptogramins B, featuring ...
Hidrogel de goma de alfarroba contendo nanocápsulas de disseleneto de difenila para o tratamento da tricomoníase vaginal
(Universidade Federal de Santa Maria, 2021-09-27)
Trichomoniasis is a sexually transmitted infection (IST) whose vector is the parasite Trichomonas vaginalis.
Conventional therapies have, in most cases, low efficacy and high toxicity, making the search for new therapies ...