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Atividade antimicrobiana do óleo essencial de camomila romana (Chamaemelum nobile)
(Universidade Federal de Santa Maria, 2019-03-11)
The increased prevalence of infections by multiresistant microorganisms has drawn
the attention of the scientific community to the need for new antimicrobial drugs. At the
same time, the perception of the inevitability ...
Desenvolvimento de nanocápsulas poliméricas com diferentes revestimentos para a liberação cerebral de vimpocetina
(Universidade Federal de Santa Maria, 2018-02-02)
Vinpocetine (VP) is used in neurodegenerative diseases, and researches have
indicated a promising anticonvulsant effect of this drug. However, it shows some limitations as
low aqueous solubility and short half-life. ...
Reposicionamento dos antidepressivos fluoxetina e paroxetina e efeitos sinérgicos com ciprofloxacino frente bactérias multidroga resistentes
(Universidade Federal de Santa Maria, 2020-08-28)
The growing need for effective antimicrobial agents for the treatment of multidrug-resistant bacteria (MDR), mainly caused by nosocomial infections, leads to the use of alternative alternatives. The repositioning or ...
Desenvolvimento de sistemas microparticulados a partir da blenda Eudragit® L100 e goma gelana para liberação oral de cetoprofeno
(Universidade Federal de Santa Maria, 2017-08-30)
Ketoprofen is a non-steroidal anti-inflammatory drug with analgesic and antipyretic properties. However, this drug has a short half-life, and causes adverse effects on the gastrointestinal tract by limiting its application ...
Avaliação anti-inflamatória e antioxidante do extrato de tucumã (Astrocaryum aculeatum): estudos in vitro e in vivo
(Universidade Federal de Santa Maria, 2018-01-19)
With the rise of new concepts such as functional foods, nutraceuticals and phytomedicines, allied to the use of traditional medicine, products of plant origin are in evidence. Brazil is a highlight in the development of ...
Avaliação de métodos na produção de biofilme em Staphylococcus spp. isolados de hemoculturas de unidade de terapia intensiva adulta
(Universidade Federal de Santa Maria, 2017-09-27)
Intensive Care Units (ICUs) are intended for the care of critically ill patients who need continuous monitoring and support of their vital functions. These are 5 to 10 times more likely to contract with Bloodstream Infections, ...
Características genotípicas e fenotípicas de cepas de Escherichia coli isoladas de carne moída bovina in natura
(Universidade Federal de Santa Maria, 2016-01-15)
Escherichia coli is a bacterium that comprise the normal intestinal flora of warm-blooded
animals, responsible for a variety of diseases in humans, as bacteremia, urinary tract and
intestinal infections. Some become ...
Estudo de toxicidade aguda e subaguda do extrato bruto das cascas de Luehea divaricata Mart. em ratos wistar
(Universidade Federal de Santa Maria, 2015-12-14)
The species Luehea divaricata Martius belongs to the Malvaceae family and is popularly known as "açoita-cavalo." It occurs naturally in northeastern Argentina, eastern Paraguay and northern Uruguay. In Brazil, predominates ...
Filmes de pullulan contendo nanocarreadores de óleo de romã: uma abordagem promissora para o tratamento de desordens cutâneas e vaginais
(Universidade Federal de Santa Maria, 2020-11-06)
The aim of this study was to develop Pullulan films (PUL) containing pomegranate seed oil nanocarriers for the cutaneous treatment of atopic dermatitis and vaginal application for the management of vulvovaginal candidiasis ...
Avaliação de parâmetros de estresse oxidativo em gestantes gemelares
(Universidade Federal de Santa Maria, 2018-01-05)
Twin pregnancies are considered to be of high obstetric risk due to several morbidities frequently present due to the increased supply of metabolic compounds to fetuses and the high oxygen consumption by the fetus-placenta ...