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Atividade radioprotetora, perfil toxicológico e efeito contra a toxicidade da ciclofosfamida do extrato de tucumã: estudos in vitro e in vivo
(Universidade Federal de Santa Maria, 2020-08-04)
Cancer is a multifactorial disease characterized by loss of control of cell division. Nowadays, it is a serious health problem worldwide, leading to many deaths every year. Current treatments for cancer include radiation ...
Avaliação dos efeitos de curcumina e silimarina sobre a toxicidade induzida por micotoxinas in vitro e in vivo
(Universidade Federal de Santa Maria, 2020-10-08)
Mycotoxins are secondary metabolites produced by fungi and represent a worldwide concern
due to their global distribution and the harmful effects caused by their ingestion. This problem
presents itself in its most dramatic ...
Estresse oxidativo e metabolismo ósseo em modelo roedor de síndrome dos ovários policísticos (SOP)
(Universidade Federal de Santa Maria, 2020-12-18)
Polycystic ovary syndrome (PCOS) is considered the commonest cause of endocrine infertility in women and affects around 8% of females at reproductive age. It is a complex disturbance, frequently associated with insulin ...
Relação entre o sistema imune e o comportamento em zebrafish
(Universidade Federal de Santa Maria, 2020-03-06)
The interaction between immune system and behavior has already been observed in several studies using mammals as animal model. On the other hand, this relationship has not yet been clearly demonstrated in other animal ...
Efeitos do tipo ansiolítico e antiestresse da taurina em peixe-zebra (Danio rerio)
(Universidade Federal de Santa Maria, 2020-03-24)
Mental disorders are a major challenge to global health, considered 21st century pandemics. About a third of the world's disability is caused by mental health problems. Faced with this situation, World Health Organization ...
Influência benéfica da estimulação tátil em modelos experimentais de depressão: parâmetros neuroquímicos e comportamentais em ratos
(Universidade Federal de Santa Maria, 2020-10-20)
Depression is a common disease worldwide and although there are several drugs for the treatment of depression, the effectiveness of this pharmacotherapy still presents limitations, possibly due to the difficulty of ...
O extrato hidroalcóolico das folhas de Arachis hypogaea L (Fabaceae) produz atividade antioxidante e anti-inflamatória in vitro sem a indução de toxicidade in vitro ou in vivo
(Universidade Federal de Santa Maria, 2020-03-26)
Arachis hypogaea (peanut) leaves are traditionally used for the treatment of insomnia and inflammation. This study aimed to examine the phytochemical composition of peanut leaf hydroalcoholic extract (PLHE) and to describe ...
Minociclina e imunoterapia no tratamento da pitiose experimental em coelhos
(Universidade Federal de Santa Maria, 2020-03-31)
Pythiosis is a chronic disease caused by the oomycete Pythium insidiosum that
affects both animals and humans. The main animals affected are the equines and canines,
generating a worrying clinical picture. If not identified ...
Aplicações do óleo essencial de aloysia citriodora paláu e do citral adicionados à água e à dieta para jundiá e carpa-capim
(Universidade Federal de Santa Maria, 2020-03-20)
The present study deals with the effectiveness of citral added to water as a sedative and anesthetic in silver catfish (Rhamdia quelen) and grass carp (Ctenopharyngodon idella). It deals with the anesthetic safety of the ...
Avaliação do polimorfismo da Ala16ValMnSOD e dos parâmetros bioquímicos no déficit cognitivo na epilepsia
(Universidade Federal de Santa Maria, 2020-03-09)
Epilepsy is a chronic neurological condition, characterized by recurrent epileptic
seizures that can cause neurochemical, cognitive and psychological changes. The
mechanisms of action associated with epilepsy can involve ...