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Efeitos do consumo de ácidos graxos n-3, n-6 e trans sobre aspectos bioquímicos e moleculares em um modelo animal de mania
(Universidade Federal de Santa Maria, 2014-07-18)
Fatty acids (FA) are constituents of neuronal phospholipid membranes, where they are essential for the development and functioning of the brain. During the peak of neuronal growth, occurring during the last week of gestation ...
Ação protetora do licopeno sobre as alterações induzidas pela micotoxina zearalenona em camundongos machos
(Universidade Federal de Santa Maria, 2014-12-22)
Zearalenone (ZEA) an estrogenic mycotoxin and, therefore the reproductive system as one of its main targets of toxicity. Besides being a mycotoxin and toxigenic immunosuppressive, the ZEA hematological changes and promotes ...
Associação do polimorfismo MnSOD ALA16VAL com os biomarcadores inflamatórios, apoptóticos e BDNF em pacientes após acidente vascular encefálico tardio
(Universidade Federal de Santa Maria, 2017-07-01)
Stroke is one of the most frequent neurologic diseases and involves various risk factors such as atherosclerosis, dyslipidemia and diabetes mellitus. Furthermore, the mechanisms of action associated with the pathophysiology ...
Influência do manuseio neonatal sobre parâmetros comportamentais, bioquímicos e moleculares após o uso de drogas psicoestimulantes em ratos
(Universidade Federal de Santa Maria, 2016-09-21)
The abusive use of psychostimulant drugs is a common social problem in countries of different cultures, with increasing and alarming incidence, whose discontinuance of use is associated with anxiety and depression cases. ...
Óleos essenciais de Myrcia sylvatica (G. Mey.) DC. e Curcuma longa L. como anestésicos para peixes: efeitos sobre as respostas fisiológicas
(Universidade Federal de Santa Maria, 2016-12-16)
The use of anesthetic substances is necessary to reduce stress and provide fish welfare during aquaculture
practices. The aim of this study was to investigate the use of Myrcia sylvativa (EOMS) and Curcuma longa
(EOCL) ...
Efeito do desbalanço genético e farmacológico do metabolismo oxidativo em indicadores de fertilidade masculina
(Universidade Federal de Santa Maria, 2016-12-07)
Previous studies indicate that changes in oxidative metabolism may play a role in reproductive
success. Manganese-dependent superoxide dismutase enzyme (SOD2), a key in the oxidative
balance, presents a genetic variation ...
Influência de Harpagophytum procumbens sobre parâmetros comportamentais e moleculares em um modelo de discinesia orofacial em ratos
(Universidade Federal de Santa Maria, 2017-02-18)
Fluphenazine is a typical antipsychotic used for the treatment of schizophrenia. However, its chronic use has been related to the appearance of extrapyramidal side effects, such as tardive dyskinesia (TD). Studies suggest ...
Interação entre o brometo de piridostigmina e o desbalanço superóxido-peróxido de hidrogênio na cito-genotoxicidade de células neurais e imunes mononucleares
(Universidade Federal de Santa Maria, 2018-06-11)
Pyridostigmine bromide (PB) is a reversible acetylcholinesterase inhibitor (AChE), and the first line of
symptoms associated with neuromuscular junction disorders (JNM) and has been used prophylactically
in the Persian ...
Citral como aditivo na dieta de peixes estuarinos: perfil redox, imunidade inata e parâmetros hepáticos
(Universidade Federal de Santa Maria, 2019-06-27)
Citral is a monoterpenoid that occurs in essential oils of different plant species used in folk medicine, which also showed promising effects when added to fish diets. However, in spite of the numerous biological activities ...
Influência da suplementação de diferentes ácidos graxos sobre o fotodano da pele induzido pela exposição de roedores à radiação ultravioleta
(Universidade Federal de Santa Maria, 2014-02-18)
Diet fatty acids (FA) are fundamental to the phospholipids structure and function of cell membranes, in which long chain polyunsaturated FA (PUFA) increase its fluidity, while the trans FA (TFA) to make it more rigid. Also, ...