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Itens para a visualização no momento 21-30 of 48
Benznidazol livre e nanoestruturado na terapia da Doença de Chagas experimental e seus efeitos sobre biomarcadores do sistema colinérgico e estresse oxidativo
(Universidade Federal de Santa Maria, 2022-01-27)
Chagas disease (CD) is widely distributed in Latin America, caused by Trypanosoma cruzi. The infection promotes an inflammatory process, which triggers several factors of the immune response. The cholinergic system acts ...
O extrato hidroalcóolico das folhas de Arachis hypogaea L (Fabaceae) produz atividade antioxidante e anti-inflamatória in vitro sem a indução de toxicidade in vitro ou in vivo
(Universidade Federal de Santa Maria, 2020-03-26)
Arachis hypogaea (peanut) leaves are traditionally used for the treatment of insomnia and inflammation. This study aimed to examine the phytochemical composition of peanut leaf hydroalcoholic extract (PLHE) and to describe ...
Mecanismos neurológicos e sistêmicos envolvidos na patogênese da listeriose e impactos do uso de curcumina livre e nanoencapsulada na infecção in vivo
(Universidade Federal de Santa Maria, 2021-10-27)
Foodborne zoonotic disease, listeriosis contains numerous gaps in knowledge regarding its pathogenic mechanisms. In addition, the problem of bacterial resistance requires potential alternatives to treatment. The aim of ...
Infecção por Aeromonas hydrophila em jundiá: estresse e efeito terapêutico da combinação de florfenicol com linalol via banho
(Universidade Federal de Santa Maria, 2022-01-11)
The first article consisted of a review article whose objective was to synthesize the current knowledge regarding the effects of aeromonosis on fish oxidative status. The second article consisted of an original article ...
Avaliação do efeito de rutina e curcumina em marcadores oxidativos, hematológicos e purinergicos em ratos com hiperlipidemia induzida
(Universidade Federal de Santa Maria, 2022-08-05)
The accumulation of lipids, such as total cholesterol, triglycerides, and LDL, in
the bloodstream is known as hyperlipidemia. This condition is characterized by
generating inflammatory and oxidative damage both in blood ...
Efeito antioxidante e imunomodulador de um multissuplemento à base de guaraná, selênio e L-carnitina em modelos in vitro, in vivo e em pacientes com esclerose múltipla
(Universidade Federal de Santa Maria, 2022-08-19)
Multiple sclerosis (MS) is an autoimmune, demyelinating, and neurodegenerative disease, which has neuroinflammation and oxidative stress as key parts of its pathogenesis. Among the clinical forms of the disease, is ...
Modelos de toxicidade da cisplatina em ratos adolescentes: papel protetor do disseleneto de difenila e do ebselen e avaliação da co-exposição ao estresse
(Universidade Federal de Santa Maria, 2022-04-19)
Cisplatin is a recommended chemotherapy drug for the treatment of pediatric and adult
neoplasms that, despite its wide use, is related to numerous serious adverse effects
such as neurotoxicity. In animal models using ...
Participação do receptor de potencial transitório anquirina 1 e disfunção mitocondrial em um modelo de fibromialgia em camundongos
(Universidade Federal de Santa Maria, 2022-09-30)
Fibromyalgia is a painful condition associated with several comorbidities. Although the
mechanism underlying fibromyalgia remains unknown, monoamine depletion, reactive oxygen
species (ROS) overproduction, and mitochondrial ...
Efeito do estresse térmico em leucócitos bovinos durante o reconhecimento materno da gestação
(Universidade Federal de Santa Maria, 2022-11-01)
Heat stress represents one of the major causes of productive and reproductive losses in
a milk production system. Heat stress induces hyperthermia, alters folliculogenesis, reduces the
expression of estrus signals, causes ...
Efeitos toxicológicos neonatal, transgeracional e crônico de piretroides em Caenorhabditis elegans
(Universidade Federal de Santa Maria, 2022-12-16)
The extensive use of domestic and agricultural insecticides to control domestic, crop and
even zootechnical pests has been growing in recent years. One of the main classes used
in the composition of insecticides are the ...