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Envolvimento de fatores oxidativos e inflamatórios sobre a resistência ao tratamento com fluoxetina em um modelo de depressão em camundongos
(Universidade Federal de Santa Maria, 2021-10-27)
Major depression (DM) is among the most disabling mental disorders in the world. According to the World Health Organization (WHO), more than 300 million people are affected by DM. The disorder is characterized by a set of ...
Efeito do beta-cariofileno na suscetibilidade hepática e renal à aflatoxina B1 em parâmetros bioquímicos, oxidativos e moleculares em ratos
(Universidade Federal de Santa Maria, 2021-08-13)
Aflatoxin B1 (AFB1) is a mycotoxin produced manly by Aspergillus flavus and Aspergillus
parasiticus fungi. Among the existing mycotoxins, AFB1 has been the most studied due to its
high toxigenic potential. Exposure to ...
O extrato hidroalcóolico das folhas de Arachis hypogaea L (Fabaceae) produz atividade antioxidante e anti-inflamatória in vitro sem a indução de toxicidade in vitro ou in vivo
(Universidade Federal de Santa Maria, 2020-03-26)
Arachis hypogaea (peanut) leaves are traditionally used for the treatment of insomnia and inflammation. This study aimed to examine the phytochemical composition of peanut leaf hydroalcoholic extract (PLHE) and to describe ...
Infecção por Aeromonas hydrophila em jundiá: estresse e efeito terapêutico da combinação de florfenicol com linalol via banho
(Universidade Federal de Santa Maria, 2022-01-11)
The first article consisted of a review article whose objective was to synthesize the current knowledge regarding the effects of aeromonosis on fish oxidative status. The second article consisted of an original article ...
Efeito antioxidante e imunomodulador de um multissuplemento à base de guaraná, selênio e L-carnitina em modelos in vitro, in vivo e em pacientes com esclerose múltipla
(Universidade Federal de Santa Maria, 2022-08-19)
Multiple sclerosis (MS) is an autoimmune, demyelinating, and neurodegenerative disease, which has neuroinflammation and oxidative stress as key parts of its pathogenesis. Among the clinical forms of the disease, is ...
Efeitos toxicológicos neonatal, transgeracional e crônico de piretroides em Caenorhabditis elegans
(Universidade Federal de Santa Maria, 2022-12-16)
The extensive use of domestic and agricultural insecticides to control domestic, crop and
even zootechnical pests has been growing in recent years. One of the main classes used
in the composition of insecticides are the ...
Envolvimento do receptor TRPA1 na nocicepção e neuroinflamação observada em modelos de esclerose múltipla em camundongos
(Universidade Federal de Santa Maria, 2022-05-03)
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS), and neuropathic pain and headache are significant sensory alterations that are difficult to manage in these patients. In the different ...
Efeitos do aspartame e do orlistate em animais saudáveis e com doença gordurosa do fígado associada a disfunção metabólica: parâmetros bioquímicos, metabólicos e oxidativos
(Universidade Federal de Santa Maria, 2023-01-18)
This thesis evaluated the effects of chronic administration of aspartame (ASP), as well as investigated
the effects of ASP, orlistat, and their association in the liver of healthy mice and mice with metabolicassociated ...
Suplementação dietética com nerolidol melhora a capacidade antioxidante e perfil de ácidos graxos musculares de Brycon amazonicus expostos a estresse por calor
(Universidade Federal de Santa Maria, 2023-03-21)
Aquaculture plays an important role in providing food for a growing world population, with
fish being an important food item in the human diet throughout history. However, the increase
in water temperature is a worrying ...
Avaliação da influência da dieta em parâmetros de estresse oxidativo, inflamação e modificações epigenéticas em pacientes com lúpus eritematoso sistêmico
(Universidade Federal de Santa Maria, 2023-10-11)
Exacerbated cellular activation due to autoimmunity in Systemic Lupus Erythematosus (SLE)
can generate an imbalance between antioxidants and pro-oxidants, triggering oxidative stress.
In addition to oxidative stress, ...