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Mecanismos bioquímicos e moleculares envolvidos em efeitos comportamentais induzidos por reserpina em ratos e C. elegans com ênfase em parâmetros oxidativos e dopaminérgicos
(Universidade Federal de Santa Maria, 2015-01-16)
Animal models as reserpine are helpful to understand the pathophysiology of several diseases with involuntary movements, as Parkinson s disease (PD), and to search efficient treatments. The present study tested the effects ...
Efeito do extrato de Syzygium cumini e alterações provocadas pela síndrome metabólica sobre parâmetros bioquímicos e inflamatórios
(Universidade Federal de Santa Maria, 2013-12-04)
Metabolic syndrome (MetS) is a complex disorder represented by a set of cardiovascular risk factors, including endothelial dysfunction, oxidative stress and inflammation. Syzygium cumini has hypoglycemic, anti-inflammatory, ...
Papel da Na+, K+ - ATPase no modelo de epilepsia do lobo temporal em camundongos
(Universidade Federal de Santa Maria, 2015-03-16)
Epilepsy is a disease that affects about 1-2% of the general population. Considering the high number of patients with epilepsy who are refractory to currently available drugs, it is important to search for new anticonvulsant ...
Óleos essenciais como anestésicos para peixes: aspectos bioquímicos e moleculares
(Universidade Federal de Santa Maria, 2015-01-15)
The essential oil (EOs) extracted from plants Hesperozygis ringens and Lippia alba possess
anesthetic and sedative properties and is an alternative to traditional anesthetics used in
aquaculture for ease of handling ...
Richardia brasiliensis Gomes: composição fitoquímica, atividade biológica e toxicidade
(Universidade Federal de Santa Maria, 2022-07-22)
Medicinal plants are used both in chemoprevention and in the treatment of a disease after it has already
been installed. In general, despite the wide use, knowledge about the phytochemical composition,
biological activities, ...
Efeito antioxidante e imunomodulador de um multissuplemento à base de guaraná, selênio e L-carnitina em modelos in vitro, in vivo e em pacientes com esclerose múltipla
(Universidade Federal de Santa Maria, 2022-08-19)
Multiple sclerosis (MS) is an autoimmune, demyelinating, and neurodegenerative disease, which has neuroinflammation and oxidative stress as key parts of its pathogenesis. Among the clinical forms of the disease, is ...
Efeitos do extrato bruto de Sida rhombifolia L. sobre marcadores de toxicidade em diferentes modelos experimentais
(Universidade Federal de Santa Maria, 2022-08-23)
The use of medicinal plants is on the rise for different reasons, from a search for health as a whole, disease prevention and maintenance of well-being, vitality and quality of life. Sida rhombifolia (Malvaceae), a plant ...
Efeito genômico de bebidas ricas em cafeína e catequinas na modulação de marcadores oxidativos e inflamatórios associados a imunossenescência
(Universidade Federal de Santa Maria, 2021-12-10)
Introduction: Brazil has shown an accelerated aging process when compared to other countries in the world, a fact that directly impacts health and social care systems, as biological aging is associated with dysfunctions ...
Atividade cicatrizante do cubiu (Solanum sessiliflorum) e do campo magnético
(Universidade Federal de Santa Maria, 2022-04-29)
Skin healing is a complex and distinct process, in which treatments aimed at favoring and accelerating it, such as the therapeutic use of magnetic fields, are beneficial. However, the role of magnetic fields in the oxidative ...
Impactos neuroendócrinos e comportamentais de um inseticida à base de imidacloprid em zebrafish
(Universidade Federal de Santa Maria, 2022-09-16)
Zebrafish is a well-established model organism for translational and ecotoxicological research. Despite having the genome completely sequenced and the behavior and physiology well reported, there are some issues related ...